Vaccination Against COVID-19 in Chronic Kidney Disease

Patients on dialysis and kidney transplant patients infected with SARS-CoV-2 (severe acute
respiratory syndrome coronavirus type 2) have an increased risk to develop a more severe
course of disease or die from COVID-19 (coronavirus disease 2019). SARS-CoV-2 vaccination can
increase protection against COVID-19. Kidney transplant patients and patients requiring
dialysis suffer from an acquired immune deficiency. Due to the dysfunctional immune response,
the general vaccine response in dialysis patients and kidney transplant patients is in many
cases insufficient.

Until now, the vaccination response in dialysis patients and kidney-transplanted patients is
unpredictable. Verification of vaccine response can provide important information on how to
treat and protect these patients from a COVID-19. Therefore, there is a medical need to
monitor vaccine protection after SARS-CoV-2 vaccination in clinical practice. In this
observational study, data of the SARS-CoV-2 vaccination response collected in clinical
routine will be analyzed from these patients. Based on this observational study, the
investigators aim to get first evidence whether and to what extent vaccination against
COVID-19 causes a vaccine response in immunocompromised patients with kidney disease.