Vaccination Against COVID-19 in Chronic Kidney Disease

Patients on dialysis and kidney transplant patients infected with SARS-CoV-2 (severe
acute respiratory syndrome coronavirus type 2) have an increased risk to develop a more
severe course of disease or die from COVID-19 (coronavirus disease 2019). SARS-CoV-2
vaccination can increase protection against COVID-19. Kidney transplant patients and
patients requiring dialysis suffer from an acquired immune deficiency. Due to the
dysfunctional immune response, the general vaccine response in dialysis patients and
kidney transplant patients is in many cases insufficient.

Until now, the vaccination response in dialysis patients and kidney-transplanted patients
is unpredictable. Verification of vaccine response can provide important information on
how to treat and protect these patients from a COVID-19. Therefore, there is a medical
need to monitor vaccine protection after SARS-CoV-2 vaccination in clinical practice. In
this observational study, data of the SARS-CoV-2 vaccination response collected in
clinical routine will be analyzed from these patients. Based on this observational study,
the investigators aim to get first evidence whether and to what extent vaccination
against COVID-19 causes a vaccine response in immunocompromised patients with kidney
disease.