Official Title
The Use of Angiotensin Converting Enzyme Inhibitors and Incident Respiratory Infections, Are They Harmful or Protective? An Analysis Using UK Based Electronic Health Records of 5.6 Million Individuals.
Brief Summary

The study use UK based linked electronic health records from the Clinical Research Datalink (CALIBER) of 5.6 million individuals to conduct a matched case-control study to investigate the incidence of influenza in individuals prescribed ACEI compared to those not prescribed ACEI.

Status
Unknown status
Conditions
Covid-19, Coronavirus, Angiotensin Converting Enzyme Inhibitors, Influenza, Electronic Health Records, Epidemiology, Comorbidity, Incidence, United Kingdom
Interventions

Drug: ACE inhibitor

Any prescription of ACE inhibitor

Eligibility Criteria

Inclusion Criteria:

- We identify individuals aged 18 years or older and registered in the current primary
care practice for at least one year.

Exclusion Criteria:

- We exclude individuals with a prior history of influenza and viral pneumonia before
study entry.

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: N/A
Sponsors / Collaborators
University College, London
NCT Number
NCT04322786
MeSH Terms
Respiratory Tract Infections
Angiotensin-Converting Enzyme Inhibitors