Among patients with SARS-CoV-2 pneumonia, approximately 20% have an acute kidney injury (AKI) and 5% require renal replacement therapy. Occurrence of AKI in patients with COVID-19 is associated with increased morbidity and mortality. Early detection of patients at risk of AKI would allow to prevent onset or worsening of AKI. The aim of this study is to determine if urine biomarkers of renal tubular damage such as TIMP-2 and IGFBP7 could early identify patients with SARS-CoV-2 pneumonia at risk of developing AKI.
Other: [TIMP-2]*[IGFBP-7]
[TIMP-2]*[IGFBP-7] mesurement in urine sample relicates of COVID-19 patients admitted to the Montpellier University Hospital
Inclusion criteria:
- Age ≥ 18 years
- COVID-19 confirmed by positive SARS-CoV-2 PCR
- at least one urine sample
Exclusion criteria:
- Persons under protection
- Paritcipation rejections
Uhmontpellier
Montpellier, France
Romaric Larcher, MD, PharmD, MSc, Principal Investigator
UH Montpellier