Official Title
Timing of Tracheotomy in Covid-19 Positive Patients: a Randomized, Controlled Trial
Brief Summary

Critically ill covid-19 patients may require respiratory support including mechanical ventilation. After an initial period with an endotracheal tube, a tracheotomy is performed in order to reduce potential airway complications, reduce the need of sedation and facilitate the monitoring and recovery. The optimal timing of this surgical procedure is, however, still unknown. The aim of this randomized, controlled trial is to compare the outcome of early (within 7 days after intubation) vs late (at least 10 days after intubation) tracheotomy in covid-19 patients. The need for mechanical ventilation, sedation, additional oxygen support, frequency of complications, duration at the ICU and mortality through the ICU stay will be evaluated and compared.

Completed
COVID-19
ARDS
Tracheostomy Complication
Respiratory Insufficiency
Corona Virus Infection

Procedure: Tracheotomy

Surgical procedure to secure airway

Eligibility Criteria

Inclusion Criteria:

- Verified Covid-19 infection

- Intubated due to respiratory insufficiency and need for mechanical ventilation

- Informed consent from patient or relative

Exclusion Criteria:

- Age below 18 years

- Need for mechanical ventilation less than 14 days

- Tracheotomy not possible within 7 days

- Tracheotomy not possible due to anatomical or other medical reasons

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: N/A
Countries
Sweden
Locations

Sahlgrenska University Hospital
Gothenburg, Sweden

Henrik Bergquist, Assoc Prof, Principal Investigator
Sahlgrenska University Hospital, Sweden

Sahlgrenska University Hospital, Sweden
NCT Number
Keywords
Covid-19
Tracheotomy
Tracheostomy
RCT
ARDS
MeSH Terms
COVID-19
Coronavirus Infections
Respiratory Insufficiency