Seroprevalence study of COVID-19 in Saint Petersburg, Russia is a regional longitudinal cohort study aiming to evaluate the spread dynamics of the COVID-19 disease in the population of Saint Petersburg. Clinically asymptomatic adults are sampled from the population using random digit dialing and tested for the presence of SARS-CoV-2-specific antibodies in the blood serum. Data collection and serial sampling of the same individuals spans four weeks and is conducted every two weeks in order to understand both the spread of the virus in the population.
At least 1 000 individuals, 18 years old and older, are randomly sampled using random digit
dialing from the population of Saint Petersburg, Russia. Random sampling is performed by a
survey company on the list of mobile phone numbers with designated geography prefixes of St.
Petersburg. The baseline questionnaire for computer-assisted telephone interview includes
travel history, medical history, and socio-economic status of the respondents. Sampled
individuals are then invited to the clinic for blood sampling, their refusal to participate
is recorded. Collected blood samples are used for SARS-CoV-2-specific antibodies testing.
Data and sample collection spans four weeks and is conducted every two weeks. Participants
complete additional questionnaires in the clinic providing information on medical history,
history of allergies, chronic disease, smoking, and medication taken regularly. Contact
tracing data and environmental conditions of the household are reсorded.
Inclusion Criteria:
- Individuals sampled from the population of Saint Petersburg, Russia using random digit
dialling.
- Subjects aged 18 and older of both genders.
- Asymptomatic at the time of blood draw.
- Written informed consent for a blood draw, SARS-COV-2 antibody test, and data
collection.
Exclusion Criteria:
- Presence of fever or cough or respiratory distress at the time of blood test not
attributable to other known chronic disease.
- Age under 18.
- Any health condition that may be a contraindication towards blood sampling in
out-patient clinic.
- Residence in Kolpinskiy, Kurortniy, Krasnoselsky, Kronshtadtskiy, Petrodvorcoviy,
Pushkinskiy districts of St. Petersburg.
Clinic "Scandinavia"
Saint Petersburg, Russian Federation
Lubov Barabanova, MD, Principal Investigator
Clinic "Scandinavia"