In mid-February 2020, within the Oise (France) cluster, a case of COVID-19 disease caused by a SARS-CoV2 infection was described among the personnel of the Creail Air Force Base (BA110). This resulted in the beginning of an epidemic controlled by epidemiological measures. One month later, containment measures were taken at the national level, measures that also applied to BA110 personnel. These personnel, exposed to both the initial phase of the epidemic and national protection measures, represent an extremely interesting population for understanding the epidemiological dynamics of the virus, particularly at a time when France is lifting the containment measures. It becomes extremely important to understand the levers of viral spread in order to adjust the health measures to be maintained as best as possible. The main objective of this study is to determine the extent of virus diffusion in this highly circulating population, as evidenced by several identified cases of COVID-19.
Diagnostic Test: Anti-SARS-CoV2 Serology
The anti-SARS-CoV2 serological status will be measured on a blood sample collected at Day 0.
Behavioral: Questionnaire
Epidemiological data will be collected in a questionnaire that will be filled by participants at Day 0 (Visit 1), after 3 months (Visit 2) and after 9 months (Visit 3).
The questionnaire includes:
medical data (height, weight, smoking, history of intense stress);
socio-demographic data (age, gender, civil/military status, function/occupation, rank category, army, family status/home composition, housing conditions, etc.);
clinical data : history of symptoms suggestive of COVID-19 in the last 3 months, current symptoms suggestive of COVID-19;
use of care, hospitalization, work stoppage in the last 3 months;
contact with people who are symptomatic or proven COVID-19.
Diagnostic Test: Anti-SARS-CoV2 serological controls and serum neutralization
Serological controls and a serum neutralization test will be performed on blood samples collected 3 months (Visit 2) and 9 months (Visit 3) after Day 0, respectively.
Inclusion Criteria:
- Active military or civilian defence personnel working on the Creil Air Force Base
(BA110) during the period of interest (from February 1st 2020 to the end of the study)
Exclusion Criteria:
- Contraindication to blood sampling
- Pregnant, parturient, breastfeeding woman
24e antenne médicale de Creil
Creil, France