Official Title
A Double-blind, Placebo-controlled, Phase 2 Trial of Sublingual Low-Dose Thimerosal in Adults With Symptomatic SARS-CoV-2 Infection
Brief Summary

Clinical trial to compare sublingual low does thimerosal in adults that have symptoms of SARS-CoV-2 Infection against placebo to show a difference in physical characteristics and viral levels.

Completed
SARS-CoV-2 Infection

Drug: BTL-TML-COVID

Sublingual dosing of BTL-TML-COVID on days 1 and 2 - Day 1 - 1 drop every 15 minutes for the first hour of initiation of treatment then every hour for the balance of the day until bedtime.
Day 2 - 1 drop every 2-3 hours for a total of 6 times during the day. The parallel group assignment will only be maintained until the completion of a minimum of 48 hours of blinded study drug dosing, at which point all subjects will receive the active treatment.
Day 3 - 1 drop every 15 mins for the first hour of the day, then every hour for the balance of the day until bedtime.
Days 4 through 10 - 1 drop every 3-4 hours for a total of four times during the day.

Drug: Placebo

Sublingual dosing of matching placebo on days 1 and 2 - Day 1 - 1 drop every 15 minutes for the first hour of initiation of treatment then every hour for the balance of the day until bedtime.
Day 2 - 1 drop every 2-3 hours for a total of 6 times during the day. The parallel group assignment will only be maintained until the completion of a minimum of 48 hours of blinded study drug dosing, at which point all subjects will receive the active treatment.
Day 3 - 1 drop every 15 mins for the first hour of the day, then every hour for the balance of the day until bedtime.
Days 4 through 10 - 1 drop every 3-4 hours for a total of four times during the day.

Eligibility Criteria

Inclusion Criteria:

- 40 years of age or older

- Provide written informed consent

- Have a SARS-COV-19 diagnostic test with positive results

Exclusion Criteria:

- Having an oxygen saturation level below 92% at baseline or currently on Oxygen therapy

- Subjects currently hospitalized

- Subjects who have received a COVID vaccination

- Subjects with a diagnosis of immunodeficiency

Eligibility Gender
All
Eligibility Age
Minimum: 40 Years ~ Maximum: N/A
Countries
United States
Locations

Intermountain Clinical Reserach
Draper, Utah, United States

Beech Tree Labs, Inc.
NCT Number
Keywords
Treatment for COVID-19
MeSH Terms
Infections
COVID-19