Official Title
Sex-Informed Data in the COVID-19 Pandemic.
Brief Summary

Sex and gender matter to health equity, especially in a pandemic. Sex (a biological attribute) and gender (a social construct) may influence an individual's susceptibility, vulnerability and exposure to infectious disease. In previous coronavirus epidemics (SARS and MERS), male sex was associated with worse outcomes. Both immune and the hemostatic response display ample sexual dimorphism. The primary aim of the study is to determine whether sex differences in biomarkers of platelet and immune function, gut microbiome, clinical characteristics, therapy, clinical cost sensitive outcomes (i.e. in-hospital transition of care, case severity, and mortality due to COVID-19) exist in patients affected by COVID-19.

Recruiting
COVID19
Eligibility Criteria

Inclusion Criteria:

- Patients with laboratory confirmed SARS-Cov-2 infection of any severity.

Exclusion Criteria:

- Pregnancy.

- Younger than 18 years of age.

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: 100 Years
Countries
Italy
Locations

Sapienza University of Rome - Policlinico Umberto I Roma
Rome, Italy

Investigator: Stefania Basili, MD
Contact: +390649972018
stefania.basili@uniroma1.it

Investigator:

Contacts

Stefania Basili, MD
0649972018
stefania.basili@uniroma1.it

University of Roma La Sapienza
NCT Number
Keywords
sex
gender
thrombosis
Immunity
Gut microbiota
MeSH Terms
COVID-19