SARS-CoV-2 has now crossed the 1 million number of cases and tens of thousands of deaths. It´s R0 has been calculated between 2 and 5.7 solely based on clinical symptoms but it is estimated to likely be higher. Serologic evidence of infection has not been analyzed.
Transverse, observational and descriptive study involving household contacts of documented
patients with COVID-19 infection: contacts will be invited to participate and a blood sample
will be drowned: IgM and IgG qualitative and quantitative measurements will be performed.
Demographic data regarding age, comorbidities, calculated time spent before and after the
patients diagnosis, isolation practices etc.
Inclusion Criteria:
1. Persons over 1 years of age.
2. .Meet COVID-19 confirmed case intradomestic contact definition:
1. Living in the same home as the patient with SARS-CoV-2 PCR test detected
(nasopharyngeal and/or oropharyngeal swab) performed in the Acute Respiratory
Infection Diagnostic Unit.
2. Living in the same home as the patient with a PCR test for SARS-CoV-2
Indeterminate (nasopharyngeal and/or oropharyngeal swab) performed in the Acute
Respiratory Infection Diagnostic Unit and that the initial patient has positive
IgM/IgG serology for SARS-CoV-2.
3. .Informed Consent.
Exclusion Criteria:
1. .Have fever, cough, pharyngeal pain or clinically have symptoms compatible with
COVID-19 at the time of recruitment.
2. .Autoimmune disease, cancer, neutropenia.
3. .Under 1 years of age.
4. .Patients who, in the investigator's opinion, should be excluded from the research
protocol.
Hospital Universitario José E. Gonzalez
Monterrey, Nuevo Leon, Mexico
Adrian Camacho-Ortiz, MD, Principal Investigator
Hospital Universitario "Dr. Jose Eleuterio Gonzalez, UANL