The medical and paramedical staff of the front-line services are potentially exposed to SARS-CoV-2. Therefore, despite the application of standard protective measures, it is possible that a certain number of these personnel have already contracted SARS-CoV-2, including in its asymptomatic form. Serological testing in this context would be useful for deploying immune healthcare workers as to limit the risk of viral infection and transmission. Therefore, it is of utmost importance to prove that the serological response entails the production of neutralizing antibodies.
Biological: Specific anti-SARS-CoV-2 antibodies
A serum sample needs to be collected from each participant upon recruitment into the investigation All samples will be tested by the rapid test (Artron, Artron Laboratories, Burnaby, Canada), IgM / IgG which is an antibody capture Immunochromatografac assay for simultaneous detection of IgM and IgG in serum or plasma for COVID -19 in samples.
All samples will be tested for total Immunoglobulins and IgG in samples for COVID-19 virus by Ortho clinical diagnostics chemiluminescent technique (Ortho, Raritan, USA).
Inclusion Criteria:
- Not previously diagnosed with COVID-19 except for convalescents
- Not currently symptomatic with fever or respiratory symptoms (cough, dyspnea)
Exclusion Criteria:
- Patients with fever or respiratory symptoms (cough, dyspnea)
- Refusal to give informed consent, or contraindication to venipuncture.
ECRRM
Cairo, Egypt
Faculty of Medicine, Cairo University
Cairo, Egypt