Official Title
Sero-epidemiological Study of the SARS-CoV-2 Virus in France: Constitution of a Collection of Human Biological Samples
Brief Summary

On January 2020, the discovery of a new coronavirus (SARS-CoV-2) was officially announced by the Chinese health authorities and the World Health Organization (WHO). Its complete genome was sequenced by the laboratory of respiratory infection viruses at the Institut Pasteur on 29 January 2020 in France. This will allow the identification of antigenic structures involved in the immune response and the development of serological diagnostic tests. Many questions are being asked about this new virus and the infection it causes, including questions about the percentage of asymptomatic and pauci-symptomatic forms. Serological studies can provide answers to these questions. There is no serological test for SARS-COV-2 yet, but the laboratory of respiratory infection viruses at the Institut Pasteur is working on its development. This study proposes to carry out a collection of samples taken from subjects who travelled to China before the epidemic outbreak or suspected of being infected with SARS-CoV-2. As soon as it is available, serology will be performed on the collected samples.

Detailed Description

On January 2020, the discovery of a new coronavirus (SARS-CoV-2) was officially announced by
the Chinese health authorities and the World Health Organization (WHO). This new virus is
presented as the causative agent of pneumonias. Its complete genome was sequenced by the
laboratory of respiratory infection viruses at the Institut Pasteur on 29 January 2020 in
France. This will allow the identification of antigenic structures involved in the immune
response and the development of serological diagnostic tests.

Many questions are being asked about this new virus and the infection it causes, including
questions about the transition from animal to human occur, the beginning of viral circulation
in humans, the period of contagiousness, the percentage of asymptomatic and pauci-symptomatic
forms. Serological studies can provide answers to these questions. There is no serological
test for SARS-COV-2 yet, but the laboratory of respiratory infection viruses at the Institut
Pasteur is working on its development.

This study proposes to carry out a collection of samples taken from subjects who travelled to
China before the epidemic outbreak or suspected of being infected with SARS-CoV-2.

As soon as it is available, serology will be performed on the collected samples.

Completed
SARS (Severe Acute Respiratory Syndrome)
COVID-19

Other: Human Biological samples

Blood samples for serological tests

Other: Human Biological samples

Blood samples, saliva, nasopharyngeal swab for serological tests

Eligibility Criteria

Inclusion Criteria:

- Affiliated with or benefiting from a Social Security system

- State of health compatible with a blood sample as defined in the protocol

Exclusion Criteria:

- Person benefiting from a legal protection measure or unable to express informed
consent to participation

- Have had an infectious episode and/or respiratory signs in the 14 days prior to the
scheduled visit (CORSER 1 and 2a, 2b)

- Have been in contact with a confirmed case of SARS-CoV-2 infection within 14 days
prior to the date of the visit.(CORSER 1 and 2a, 2b)

Eligibility Gender
All
Eligibility Age
Minimum: 5 Years ~ Maximum: N/A
Countries
France
Locations

CHU Amiens-Picardie
Amiens, France

EHPAD Villa Concorde
Asnieres sur seine, France

CHU François Mitterand
Dijon, France

Centre Hospitalier Départemental de Vendée
La Roche-sur-Yon, France

CHU Limoges
Limoges, France

Hôpital de la Croix Rousse
Lyon, France

EHPAD Les Etangs
Mennecy, France

CHRU de Nancy
Nancy, France

Hôpitaux de Brabois
Nancy, France

CHR Orléans
Orléans, France

Institut Mutualiste
Paris, France

Centre Médical de l'Institut Pasteur
Paris, France

Institut Pasteur
Paris, France

EHPAD Villa Lecourbe
Paris, France

Hôpital la Pitié Salpetrière
Paris, France

CHU Poitiers
Poitiers, France

Hôpital Pontchaillou
Rennes, France

CHU Saint-Etienne
Saint-Étienne, France

CHRU de Strasbourg
Strasbourg, France

CH de Tourcoing
Tourcoing, France

Hôpital Bretonneau
Tours, France

Bruno HOEN, Pr, Principal Investigator
Institut Pasteur

Institut Pasteur
NCT Number
MeSH Terms
COVID-19
Severe Acute Respiratory Syndrome