Official Title
Safety and Efficacy of Hydroxychloroquine for the Treatment & Prevention of Coronavirus Disease 2019 (COVID-19) Caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
Brief Summary

Coronavirus Disease 2019 (COVID-19) (previously called 2019-nCOV acute respiratory disease) is caused by SARS-CoV-2, a positive-sense single-stranded RNA virus of the coronavirus family. The coronaviruses are largely responsible for the common cold, the 2002 SARS outbreak in Guangdong, China, the 2012 MERS outbreak in Saudi Arabia, and the present COVID-19 outbreak that originated in Wuhan, China. Much has been reported by way of systemic injury caused by COVID-19 affecting the cardiovascular, hepatic, nervous systems. These conditions are likely the result of the virus overwhelming the immune system. For these reasons, the investigators wish to conduct this study using existing medications off-label, and over-the-counter supplements to support the immune response, prevent lasting injury, and hasten the recovery from COVID-19.

Withdrawn
COVID19
SARS (Severe Acute Respiratory Syndrome)

Drug: Hydroxychloroquine

Hydroxychloroquine

Dietary Supplement: Vitamins and Minerals

elemental Zinc Vitamin C Vitamin D3 N-acetylcysteine Elderberry Quercetin

Drug: Azithromycin

Azithromycin

Eligibility Criteria

Inclusion Criteria:

1) Patients must have one or more of the following:

1. confirmed diagnosis of active SARS-CoV-2 infection, diagnosed with PCR

2. continued close contact with an individual with suspected SARS-CoV-2 infection

3. at risk for SARS-CoV-2 infection in the opinion of the treating physician or Principal
Investigator.

Exclusion Criteria:

1) Patients must not have any uncontrolled disease such as:

1. cardiovascular disease

2. hepatic disease

3. renal disease

4. metabolic disease

5. other diseases or insufficiencies

Eligibility Gender
All
Eligibility Age
Minimum: N/A ~ Maximum: N/A

Philip DeFina, PhD, Principal Investigator
International Brain Research Foundation

International Brain Research Foundation
NCT Number
MeSH Terms
COVID-19
Coronavirus Infections
Severe Acute Respiratory Syndrome
Syndrome
Azithromycin
Hydroxychloroquine