Official Title
Registry for the Evaluation of Safety and Effectiveness of the Seraph 100 Microbind Affinity Blood Filter in the Therapy of COVID-19 Patients (COSA)
Brief Summary

The purpose of this registry study is to investigate the effectiveness and safety of the Seraph® 100 Microbind® Affinity Blood Filter (Seraph 100) in the treatment of COVID-19 patients.

Detailed Description

During the ongoing COVID-19 pandemic, millions of people have been infected with SARS- Cov-2
worldwide. In the absence of an approved vaccine or medical treatment, there is an emerging
need for treatment options, especially in critically ill patients. Multiple pharmacological
and non-pharmacological therapies are being investigated. In 2019, the Seraph® 100 Microbind®
Affinity Blood Filter (ExThera Medical Corporation, CA, USA) was approved for the removal of
pathogens in Europe. On April 17th the FDA granted Authorization for Emergency Use in
patients with COVID-19 admitted to the ICU with confirmed or imminent respiratory failure.

Unknown status
COVID-19

Device: Seraph 100

Seraph 100 therapy during a COVID-19 infection

Eligibility Criteria

Inclusion Criteria:

- COVID-19 infection

- Treatment with the Seraph® 100 Microbind® Affinity Blood Filter

- Voluntary consent to participate in Registry

Exclusion Criteria:

- none

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: 99 Years
Countries
Germany
Locations

Academic Teaching Hospital Brunswick
Brunswick, Lower Saxony, Germany

Hannover Medical School
Hannover, Germany

Contacts

Julius J Schmidt, Dr
+495115326319
schmidt.julius@mh-hannover.de

Jan T Kielstein, Prof
+495315952380
kielstein@yahoo.com

Medical Clinic V Nephrology, Academic Teaching Hospital Brunswick
NCT Number
MeSH Terms
COVID-19