Prospective Hospital Registry of Patients With Suspected or Confirmed Coronavirus Infection (COVID-19) and Community-acquired Pneumonia

Coronavirus-2019 disease (COVID-19) and community-acquired pneumonia are significantproblems of modern medicine. Pneumonia is the most common severe complication ofCOVID-19. But at the same time, COVID-19 is not the only cause of community-acquiredpneumonia. Moreover, pneumonia is only one of the numerous possible severe complicationsof COVID-19. Medical centers specialized for the hospital treatment of patients withsevere COVID-19 and community-acquired pneumonia were organized in different regions ofRussia during coronavirus pandemic-2020. The indications for hospitalization to one ofthese centers based in the National Medical and Surgical Center (NMSC) are: confirmed orsuspected severe COVID-19 or community-acquired pneumonia.A prospective medical registry of such patients hospitalized to NMSC, is intended toanalyze and compare their clinical and instrumental data, co-morbidity, treatment,short-term and long-term outcomes in real clinical practice.Stage 1. Hospital treatment in NMSCDuration of this stage: from the date of admission to the hospital up to the date ofdischarge from the hospital / or up to the date of death during the referencehospitalization. The date of admission to the hospital will be the date of enrollment tothe study.Evaluation of electronic health record data using the Medical Information System (MIS).Assessment of the outcomes of the hospital phase (discharge from the hospital, death) andsignificant events (acute respiratory and pulmonary failure, requiring mechanicalventilation; cardiovascular events - myocardial infarction, cerebral stroke, acute heartfailure, paroxysmal heart rhythm disturbances, bleedings, thrombosis of large vessels andthromboembolic complications). A survey of patients to clarify data on risk factors,somatic diseases, and drug therapy before hospitalization.COVID-19 was diagnosed when severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)infection was confirmed by Polymerase chain reaction (PCR). Pneumonia was confirmedaccording to computerized tomography (CT) data.Stage 2. Prospective outpatient follow-up for 24 monthsDuration of this stage: 24 months after discharge from the hospital This work will bedelivered by investigators from the National Medical Research Center for Therapy andPreventive Medicine.Evaluation of long-term outcomes and events among residents of Moscow and the MoscowRegion according to a patient survey (contact by phone for 30-60 days, 6 months, 12 and24 months after discharge from the hospital) and medical records.