Official Title
Prognostic and Clinical Impact of Cardiovascular Involvement in Patients With COVID-19 (Rilevanza Clinica e Prognostica Del Coinvolgimento Cardiovascolare Nei Pazienti Affetti da COVID-19)
Brief Summary

COVID-19 infection has been associated with numerous cardiac manifestations. Indeed, SARS-CoV-2 may impact on cardiovascular system through a direct myocardial infection or a secondary cardiac involvement due to hypoxia or metabolic supply-demand imbalance or prothrombotic inflammatory state. As a consequence of and besides acute myocardial damages, COVID-19 could also determine chronic cardiovascular consequences, with a significant impact on long-term prognosis, quality of life and functional capacity of COVID-19 survivors. On this basis, we aim to define the clinical and prognostic effects of myocardial involvement in COVID-19 patients.

Detailed Description

COVID-19 infection has been associated with numerous cardiac manifestations. Indeed,
SARS-CoV-2 may impact on cardiovascular system through a direct myocardial infection or a
secondary cardiac involvement due to hypoxia or metabolic supply-demand imbalance or
prothrombotic inflammatory state. As a consequence of and besides acute myocardial damages,
COVID-19 could also determine chronic cardiovascular consequences, with a significant impact
on long-term prognosis, quality of life and functional capacity of COVID-19 survivors.

On this basis, we aim to define the clinical and prognostic effects of myocardial involvement
in COVID-19 patients, with a 1-month and 6-month follow-up composed of clinical evaluation,
electrocardiogram, trans-thoracic echocardiogram, cardiovascular magnetic resonance, chest
computerized tomography scan and cardiopulmonary exercise test.

Unknown status
COVID19
Myocardial Injury
Cardiovascular Diseases
Heart Failure
Cardiovascular Morbidity
Eligibility Criteria

Inclusion Criteria: patients who were hospitalized for COVID-19

Exclusion Criteria: None.

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: 85 Years
Countries
Italy
Locations

Humanitas Research Hospital
Rozzano, Milan, Italy

Centro Cardiologico Monzino
Milan, Italy

IRCCS Auxologico San Luca
Milan, Italy

IRCCS San Donato
Milan, Italy

IRCCS Istituti Clinici Scientifici Maugeri
Pavia, Italy

Contacts

Giulio Stefanini, Prof.
0282247384
giulio.stefanini@hunimed.eu

Gianluigi Condorelli, Prof, Principal Investigator
Humanitas Research Hospital

Humanitas Hospital, Italy
NCT Number
Keywords
Cardiovascular involvement
Covid-19
MeSH Terms
COVID-19
Cardiovascular Diseases