Official Title
Proflaxis for Healthcare Professionals Using Hydroxychloroquine Plus Vitamin Combining Vitamins C, D and Zinc During COVID-19 Pandemia: An Observational Study
Brief Summary

Healthcare professionals mainly doctors, nurses and their first degree relatives (spouse, father, mother, sister, brother, child) who have been started hydroxychloroquine(plaquenil) 200mg single dose repeated every three weeks plus vitaminC including zinc once a day were included in the study. Study has conducted on 20th of march. Main purpose of the study was to cover participants those who are facing or treating COVID19 infected patients in Ankara.

Detailed Description

Healthcare professionals mainly doctors, nurses and their first degree relatives (spouse,
father, mother, sister, brother, child) who have been started hydroxychloroquine(plaquenil)
200mg single dose repeated every three weeks plus vitaminC including zinc once a day were
included in the study. Study has conducted on 20th of march. Main purpose of the study was to
cover participants those who are facing or treating COVID19 infected patients.PArticipants,
age, sex, BMI, smoking history, comorbid disease were also registered.

Unknown status
Pneumonitis
Coronavirus Infection

Drug: Plaquenil 200Mg Tablet

health workers under risk who took this medications
Other Name: Redoxan

Eligibility Criteria

Inclusion Criteria:

1. person who are working as health professional with contact to known COVID positive
case

2. Their first degree relatives (child, spouse or parents)

3. must be able to swallow tablets

Exclusion Criteria:

1. Already using plaquenil for other reasons (RA etc)

2. person with the diagnosis of COVID infection

3. Person with the condition may cause complications with this medication (severe CVD, av
block, already has ophtalmological complications, organ failure of any degree etc).

4. Documented allergic history to chloroquine;

5. Documented history of hematological system diseases;

6. Documented history of chronic liver and kidney diseases;

7. Documented history of cardiac arrhythmia or chronic heart diseases;

8. Documented history of retina or hearing dysfunction;

9. Documented history of mental illnesses; 10. Use of digitalis due to the previous
disease.

Eligibility Gender
All
Eligibility Age
Minimum: 20 Years ~ Maximum: 90 Years
Countries
Turkey
Locations

Istinye University Medical School
Istanbul, Turkey

Mahir M Ozmen, Professor, Principal Investigator
Istinye University

Istinye University
NCT Number
Keywords
hydroxychloroquine
Coronavirus
prophylaxis
healthcare professional
outbreak
MeSH Terms
Coronavirus Infections
Pneumonia
Hydroxychloroquine