Official Title
PCR-COVID-19 Predictors of Positivity in Patients Admitted to ICU for Respiratory Infection: A Prospective Observational Cohort Study
Brief Summary

Coronavirus 2019 (COVID-19) is a respiratory tropism virus transmitted through droplets emitted into the environment of infected persons. The symptoms can be extremely varied and the course can range from spontaneous healing without sequelae to death. Currently, the diagnosis of certainty for resuscitation patients (by definition "severe") is based on searching for a fragment of virus genetic material within the epithelial cells of the respiratory tree, up and/or down, by PCR. It is to be expected that the epidemic peak will make it difficult (if not impossible) to respect the stereotypical path that is currently in place, due to the lack of space in the specific unit. This will require optimization of care pathways and use of the specific sectors. It is therefore necessary to define the simple criteria, available from the moment patients are admitted, to predict the result of the COVID-19 PCR.

Unknown status
Infection Viral
Coronavirus
ARDS
Pneumonia
Eligibility Criteria

Inclusion Criteria:

- All patient admitted in ICU Lille Hospital and hospitalized in the unit "Emergent
Biological Risk" (REB) before a suspicion of infection with COVID-19

- Clinical infectious syndrome: fever (>38°C) or hypothermia ( 36°C), chill, fever at
home

- a severe respiratory table defined by:

- Oxygen demand > 3 L/min in the presence of significant comorbidity (pregnancy, chronic
respiratory disease, chronic heart disease, hemopathy, cirrhosis) or > 6 L/min in the
absence of comorbidity

- or a respiratory rate > 30 cycles per minute

- the need for mechanical, invasive or non-invasive ventilation

- the need for humidified high-flow oxygen therapy

Exclusion Criteria:

- Patient already included in study for first stay

- Cirrhosis CHILD C

- Major surgery in the last 7 days Minor patient

- Patient under guardianship or curatorship

- Refusal to participate

- No social security coverage.

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: N/A
Countries
France
Locations

Hôpital Roger Salengro, ICU, CHU Lille
Lille, France

Investigator:
Contact: 0320445962

Investigator:

Contacts

Julien Poissy, MD,PhD
0320444495 - +33
julien.poissy@chru-lille.fr

Julien Poissy, MD,PhD, Principal Investigator
University Hospital, Lille

University Hospital, Lille
NCT Number
Keywords
Critical care
biology of infectious agent
MeSH Terms
Infections
Communicable Diseases
Virus Diseases