Randomized, double-blind, placebo-controlled pilot study to evalaute viral load in saliva of COVID19+ patients using quantitative PCR, before and after use of active or placebo rinses
Other: CHX0.12+CPC0.05 oral rinse (PerioAidActive Control)
rinse 15 ml during 1 min during 5 days, twice daily
Other: placebo rinse
destilled water rinse 15 ml during 1 min during 5 days, twice daily
Inclusion Criteria:
1. Be positive for SARS-CoCV-2 real-time PCR test
2. SARS-CoV-2 patients positive, with home and/or hospitalized care.
3. Have a medical condition that allows them to perform a mouthwash for 1 minute.
Exclusion Criteria:
1. Pregnant.
2. People with impaired lung function who do not allow them to rinse.
3. Patients with antiviral treatment for Covid-19.
4. Patients with diseases that affect saliva, Sjogren's syndrome, and Systemic Lupus
Erythematosus.
5. Any cause of immunosuppression (primary or secondary), including HIV.
6. Chronic kidney disease 3b or older, Coronary heart disease, Uncontrolled diabetes
(Hb1Ac >7), Uncontrolled high blood pressure, Uncontrolled thyroid disease, history of
cancer less than 1 year
Escuela odontologia. Facultad de Salud Hospital del Valle
Cali, Colombia
Ruben Leon, PhD, Study Director
Dentaid SL