Official Title
SARS-CoV-2 Infections in Children and Adolescents: Course of COVID-19, Immune Responses, Complications and Long-term Consequences in Entire Households With Members Younger Than 18 Years
Brief Summary

Longitudinal study of 56 households with at least one member who had COVID-19 to compare the course of illness, immune responses, and long-term consequences of SARS-CoV-2 infection in HED patients with those of control subjects of the same age group. Complete households are investigated, including women who are pregnant when exposed to the virus and their newborn child(ren).

Status
Completed
Conditions
Hypohidrotic Ectodermal Dysplasia
Eligibility Criteria

Inclusion Criteria:

- household with one or more members registered as patient(s) in the University Hospital
Erlangen

- at least one person <18 years of age

- at least one household member who has or had a SARS-CoV-2 infection confirmed by a
positive PCR test, detection of specific antibodies against this virus, or by
development of COVID-19 symptoms after being in close contact with a person known to
be infected with SARS-CoV-2

- informed consent

Exclusion Criteria:

- missing informed consent of one or more household members

- language barriers to communication that would prevent informed consent

Eligibility Gender
All
Eligibility Age
Minimum: N/A ~ Maximum: N/A
Countries
Germany
Locations

University Hospital Erlangen
Erlangen, Germany

Investigators

Holm Schneider, MD, Principal Investigator
University Hospital Erlangen

Sponsors / Collaborators
University Hospital Erlangen
NCT Number
NCT04741412
MeSH Terms
COVID-19
Ectodermal Dysplasia
Ectodermal Dysplasia 1, Anhidrotic