Given the urgency of having guidelines for the management of COVID-19 in the current epidemic context and the lack of specific pharmacological treatment, Military Health recommends the launch of a multicenter, randomized, double-blind, interventional clinical trial. The aim of this study is to evaluate the efficacy of a combination of two treatments, low-dose doxcycline (100 mg/day) and Zinc (15 mg/day) (dietary supplement) in the primary prevention of COVID-19 infection in health care professionals in Tunisia compared to two control groups.
Drug: Doxycyclin
daily (100mg)
Inclusion Criteria:
- No self-medication with study drugs or antivirals
- Negative COVID19 diagnosis confirmed by PCR and negative Elisa antibody assay
- No signs of COVID19
- Having given consent for the study
Exclusion Criteria:
Participation in other clinical trials aimed at primary prevention of VIDOC infection19
- Liver failure
- Known allergy to the study product
- Pregnancy or breastfeeding
- Vitamin A and E treatment in progress
Military Hospital of Tunis
Tunis, Montfleury, Tunisia