The investigators will study nasopharunx microbiota composition, RNA sequences and in vitro cytokines production by peripheral blood cells of COVID-19 patients (both mild-moderate and severe cases) (comparing with convalescent patients and healthy controls).
The investigators will compare study parameters (basal) between mild-moderate and severe
COVID-19 patients and with other study groups (i.e. convalescent and healthy controls).
Nasopharunx microbiota dysbiosis, in vitro cytokines production profile, and peripheral blood
flocytometric results of the four study groups will be compared.
In vitro cytokines production will be studied and compared in Nill (No antigens) and Mitojen
(Cocktail of antigens) pre-prepared test tubes.
Other: Observation
The study parameters will be obtained at the time of recuirement (Basal)
Inclusion Criteria:
- Ability to give a written consent
Exclusion Criteria:
- In ability to give a written consent
- Using of medications that affect the results of study parameters
- Presence of malignancy or tuberculosis
Bakirkoy Dr.sadi Konuk Training and Research Hospital
Istanbul, Turkey
Bakirkoy Dr.sadi Konuk Training and Research Hospital
Istanbul, Turkey
Mehmet Hursitoglu, MD
+902129096000 - 20527
mehmet.hursitoglu@sbu.edu.tr
Mehmet Hursitoglu, MD, Principal Investigator
Basaksehir Cam and sakura Sehir Hospital