Official Title
Long Term Outcomes of Patients With COVID-19
Brief Summary

The investigators hypothesize that those with respiratory failure due to COVID-19 will have different burdens of mental and physical disability than those with respiratory failure who do not have COVID-19. Detecting these potential differences will lay an important foundation for treating long term sequelae of respiratory failure in these two cohorts.

Detailed Description

The aim of this proposal to is to understand the extent and degree of physical disability,
psychological sequelae, and cognitive dysfunction survivors of COVID-19 related critical
illness will have upon hospital discharge, 6 months, and up to one year post discharge. These
outcomes of interest will be evaluated prospectively. The investigators will perform these
measures in Covid-19 patients with respiratory failure and compare them to non-Covid-19
patients with respiratory failure. The investigators also seek to determine the risk factors
of these long-term complications in order to guide providers as to which patients should be
screened for these deficits. Finally, the investigators will examine the association of
various critical care interventions such as invasive versus noninvasive mechanical
ventilation or use of sedatives and their effects on disability and cognitive dysfunction.

Active, not recruiting
Critical Illness
Corona Virus Infection
Respiratory Failure

Other: Quality of Life

Physical disability assessment tool
Other Name: SF-36

Other: Impact Event Score

Psychological Sequelae assessment tool
Other Name: IES-R

Other: Hospital anxiety and depression scale

Psychological Sequelae assessment tool

Eligibility Criteria

Inclusion Criteria:

- adult patients admitted to the ICU

Exclusion Criteria:

- none

Eligibility Gender
Eligibility Age
Minimum: 18 Years ~ Maximum: N/A
United States

University of Chicago Medical Center
Chicago, Illinois, United States

University of Chicago
NCT Number
long term outcomes
Mechanical Ventilation
Noninvasive Ventilation
MeSH Terms
Coronavirus Infections
Respiratory Insufficiency
Critical Illness