Official Title
Long-term Follow-up Findings of Inpatients for COVID-19 Pneumonia Related to Lung Functions, Radiology and Exercise Capacity
Brief Summary

Coronavirus disease 2019 (COVID-19) is a respiratory tract infection caused by a newly emergent coronavirus (SARS-CoV-2) that can progress to severe multiorgan disease requiring hospitalization. The medium and long-term impact in survivors of COVID-19 on lung function, imaging by thoracic CT, exercise capacity, and health-related quality of life and the relation of these parameters remains to be determined.

Detailed Description

Aim: To evaluate medium to late (visit 1: 6-12 months after hospital discharge) effects of
COVID-19 on lung function, exercise capacity, thoracic CT findings, symptoms and HRQoL in
patients with confirmed diagnosis of SARS-CoV-2 infection and the relation between these
parameters.

Material and methods: Prospective cohort of subjects with laboratory and/or thoracic CT
confirmed COVID-19 who were treated as inpatients. Participants will perform spirometry, lung
diffusion capacity of carbon monoxide, 6-minute walk test (6MWT) and cardiopulmonary exercise
testing (CPET) after 6-12 months (Visit 1) of COVID-19. Clinical, laboratory and chest image
data during the COVID-19 hospitalization will be obtained from medical records.

The minimum sample size was estimated as 37 participants.

Unknown status
COVID19

Diagnostic Test: spirometry, thoracic CT, CPET, 6 minute walking test, SF-36 questionnaire

Participants will perform spirometry, lung diffusion capacity of carbon monoxide, 6-minute walk test (6MWT), Short form-36 (SF-36) questionnaire and cardiopulmonary exercise testing (CPET) after 6-12 months (Visit 1) of COVID-19. Clinical, laboratory and chest image data during the COVID-19 hospitalization will be obtained from medical records.

Eligibility Criteria

Inclusion Criteria:

- Adult patients with Covid 19 diagnosis

- Ability to read and speak

- Signed informed consent.

- Able to perform exercise testing and walking

Exclusion Criteria:

- Subjects with limited exercise capacity

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: 80 Years
Countries
Turkey
Locations

Koç University Hospital
Istanbul, Turkey

Benan Çağlayan, Prof Dr, Study Chair
Koç University Hospital Pulmonology Department

Koc University Hospital
NCT Number
Keywords
COVID19
lung functions
cardiopulmonary exercise testing
thoracic CT
6 minute walking test
Short form 36 questionnaire
MeSH Terms
COVID-19
Pneumonia