Official Title
Reduced Frequency Hemodialysis in Prevalent Patients Due to the Coronavirus Disease
Brief Summary

Facing the unusual situation imposed by the coronavirus disease, the aim of this study is to evaluate the risk and effects of less frequent hemodialysis on prevalent patients

Detailed Description

The novel coronavirus disease (COVID-19), also known as COVID-19 (and SARS-Cov2) by the World
Health Organization, is a rapidly evolving pandemic. The outbreak is expected to infect a
large portion of the world population, and a case fatality rate of 1-3% represents a
significant mortality and healthcare burden. In common with other viral diseases, mortality
is higher in elderly patients with high comorbidity.

The impressive figures of transmission in different communities underline the need for
reorganization of efforts to limit contagion, particularly in crowded settings. Hemodialysis
centres represents a specific setting in which many patients are repeatedly treated in the
same area at the same time.

Dialysis patients constitute a susceptible population because of their older age, high
comorbidity burden and their less efficient immune system. Therefore, they are more prone to
develop severe infectious diseases than the general population.. Moreover, if infected, the
requirements of specialized resources and staff is further complicated by requirements for
isolation, control and prevention, putting healthcare systems under additional strain.
Therefore, all measures to slow and to control unmanageably high incidence rates must be
taken very seriously.

The routine treatment usually requires three dialysis sessions per week Further, some
patients must travel long distances to the dialysis centre. One option to reduce the higher
risk of these patients is to reduce the frequency of dialysis sessions.However, the potential
benefits of reduced risk may be associated with higher interdialytic weight gain and
inadequate dialysis, Two factors that increase the risk of mortality. Furthermore, the impact
of reduced frequency on Anemia and Nutrition have not been extensively studied.

Unknown status
End Stage Renal Disease

Other: less-frequency hemodialysis

Patients of treatment group would be evaluated quarterly

Eligibility Criteria

Inclusion Criteria:

- More than 30 days of Chronic ambulatory in-center hemodialysis

Exclusion Criteria:

- More than three sessions a week

- amputated lower limbs

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: 85 Years
Countries
Argentina
Locations

Dialisis Madariaga
General Juan Madariaga, Buenos Aires, Argentina

Esteban L Siga, MD, Principal Investigator
Dialisis Madariaga

Dialisis Madariaga
NCT Number
Keywords
Covid-19
Dialysis
less frequency hemodialysis
Ultrafiltration rate
Anemia
Nutrition
MeSH Terms
Kidney Failure, Chronic