Official Title
Pilot Double Blinded Randomized Placebo Controlled Multi Central Clinical Trial on Inflammatory Regulation Effect of NAC on COVID-19
Brief Summary

Study times to evaluate the efficacy of N-Acetylcysteine therapy in the management of adult admitted patients with COVID-19.

Unknown status
COVID-19

Drug: N-Acetyl cysteine

150 mg/kg every 12 hours for 14 days (oral/IV) Diluted in 200 ml diluent (D5%, NS)
Other Name: NAC

Drug: Placebo

Matching placebo administered in the same schedule and volume as NAC

Eligibility Criteria

Inclusion Criteria:

- Adult above 18 years of age

- Admitted to the hospital With confirmed COVID-19 by RT-PCR test

- On oxygen supplement

Exclusion Criteria:

- Active use of NAC

- Known NAC allergy

- In the opinion of the treating team, progression of death is imminent and inevitable
within the next 24 hour, irrespective of provision treatment

- All patients enrolled in any other investigational drug studies in COVID-19.

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: N/A
Contacts

Baian Alabdulbaqi, MD
+966114670011
balabdulbaqi@ksu.edu.sa

Dr. Tariq Alhawassi
NCT Number
Keywords
NAC
MeSH Terms
COVID-19
Acetylcysteine
N-monoacetylcystine