Official Title
The Impact of Growth Hormone in Obese Cases With Covid-19
Brief Summary

The use of growth hormone in obese cases with COVID-19 may help them to recover earlier.

Detailed Description

It is well known that lymphoid organs such the thymus, the spleen and peripheral blood produce growth hormone (GH) and GH receptor is expressed on different subpopulations of lymphocytes. Many in vitro and in animal studies demonstrate an important role of GH in immunoregulation. GH stimulates T and B cells proliferation and immunoglobulin synthesis, enhances the maturation of myeloid progenitor cells and is also able to modulate cytokine response.

The use of growth hormone in obese cases with COVID-19 may help them to recover earlier.

Withdrawn
COVID19

Drug: Growth Hormone
Recombinant growth hormone will be used
Growth hormone
Other Name: Recombinant growth hormone

Drug: Placebo
Saline injection with the same amount
Placebo
Other Name: Saline

Eligibility Criteria

Inclusion Criteria:

- Obese with BMI > 30

Exclusion Criteria:

- History of hypersensitivity to GH

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years
Countries
Egypt

Emad R Issak, MD
Principal Investigator
Assalam Clinics

NCT Number
MeSH Terms
Hormones