In this study, the investigators propose to analyse the clinical data of all patients admitted in Geneva University Hospitals (HUG) or in a care center in Geneva who are diagnosed with COVID-19. CVD being one of the most important risk factors for developing a severe form of the disease, the investigators will explore the prognosis and clinical outcomes of those patients according to their CVD history as well as newly onset CVD during hospitalization. Moreover, as further evidence is needed on the use of renin-angiotensin-aldosterone system (RAAS) inhibitors for SARS-CoV-2 infected patients, the investigators will study prognosis and outcomes according to the patients' medications. Finally, the investigators propose to evaluate hospital length of stay and cost. The aim, therefore, is to collect information and scientific evidence from patients hospitalized and diagnosed positive for COVID-19, in order to evaluate if previous (or newly onset) CVD may influence outcomes and costs.
Hypothesis:
COVID-19+ hospitalized patients with preexisting CVD or newly onset CVD at time of
hospitalization have different clinical outcomes compared to those without CVD and COVID-19+.
Objectives:
The primary aim of this study is to gather observational data, starting from February 1st
2020 until the end of the pandemic, to compare clinical outcomes COVID+ hospitalized patients
at HUG or in a care center in Geneva with pre-existing or newly onset CVD, to COVID+
hospitalized patients at HUG or in a care center in Geneva without pre-existing CVD.
The secondary aims of this study are:
- To determine the association between COVID-19 disease and CVD, based on: age, previous
CV diseases, CV risks factors, CV medications (e.g. ACE Inhibitors or angiotensin II
receptor antagonists)
- To explore CVD profiles that may influence COVID-19 disease outcomes
- To determine the cause of death in CVD patients (either with preexisting CVD or newly
diagnosed with CVD)
- To understand the vulnerability of the myocardium (new event of either heart failure,
acute coronary syndrome, arrhythmia, myocarditis) in patients with COVID-19 disease.
Other: Covid-19 + patients
all the patients hospitalized in Geneva and SARS-Cov2 positive
Inclusion Criteria:
- Subject is ≥18 years of age.
- Patient diagnosed SARS-CoV-2 positive at time of hospitalization.
- In case of the subject accepting the follow-up at 30 days and 1 year, Signed Patient
Informed Consent (PIC) form
Exclusion Criteria:
- Patients unwilling to provide informed consent for the follow-up.
Geneva University Hospital (HUG)
Geneva, Switzerland