Official Title
Exploring Vaccine Confidence and Uptake of Potential COVID-19 Vaccines Among a Cross-section of US Healthcare Providers and Key At-risk Subgroups in the Rural South
Brief Summary

The COVID-19 pandemic has highlighted deleterious US health inequities. Specifically, African Americans, Latinos, and Native Americans have and continue to shoulder a greater burden of COVID-19 infections and deaths in the US. In addition to existing racial and ethnic disparities are rural health and regional disparities. Given the disproportionate impact of disease in US communities of color and also in rural and southern regions of the US, there is no doubt that these at-risk subgroups will continue to experience higher rates of coronavirus-related mortality as well as other long-term health outcomes as compared to other US populations. It is unknown how healthcare providers and other key at-risk subgroups within the US will receive COVID-19 vaccines. For success in immunizations, the US will need to reach their most at-risk and vulnerable populations. In addition to at-risk populations, a successful immunization strategy will involve engaging providers to support clear, consistent, and strong vaccine recommendation. It is critical to build vaccine trust, confidence, and overall acceptance of COVID-19 vaccines among healthcare providers and key at-risk subgroups, especially given the accelerated production timeline of these vaccines. Likewise, tailored vaccine messaging for key subgroups is vital in achieving vaccine confidence and trust. The proposed study will explore perceptions, confidence, trust, and uptake of potential COVID-19 vaccines among healthcare providers (nurses and doctors) and key at-risk population subgroups (minority populations living in the rural south) and will develop and test vaccine messaging that boosts vaccine confidence and trust among these key at-risk subgroups.

Detailed Description

Study objectives are as follows: Objective 1: To assess COVID-19 perceptions, COVID-19
vaccine confidence, projected vaccine recommendation practices, and trust in the health
system and public health authorities among a cross-section of healthcare providers in the US
(nurses and physicians); Objective 2: To assess COVID-19 perceptions, COVID-19 vaccine
confidence, projected vaccine uptake, and trust in the health system, in healthcare
providers, and in public health authorities among key at-risk subgroups in the US (minority
populations living in the rural south); and Objective 3: To develop, tailor, and test
COVID-19 vaccine messaging to boost vaccine confidence and trust, and COVID-19 preventive
behavior, among at-risk subgroups in the US (minority populations living in the rural south).
Perceptions, confidence, uptake, and trust in potential COVID-19 vaccines will be assessed
among four identified and distinct groups via a quantitative and electronic survey and
qualitative focus groups with key at-risk subgroups will be utilized to develop, tailor, and
test COVID-19 vaccine messaging for at-risk subgroups.

This study will: 1) provide important national-level data regarding healthcare provider
vaccine perceptions, confidence, trust, and projected vaccine recommendation practices for
COVID-19, 2) ascertain vaccine perceptions, confidence, trust, and projected uptake of
potential COVID-19 vaccines among at-risk populations in the US, and 3) develop tailored
messaging for at-risk populations that can be used to boost vaccine confidence and trust, and
preventive behaviors, among these high-risk groups in the coming years. This study will help
to inform a larger coordinated national promotion strategy and campaign that can work to
effectively communicate with the public about potential COVID-19 vaccines.

Recruiting
Coronavirus

Other: Survey research

This is not an intervention study. It involves social science research of surveys and focus groups.

Eligibility Criteria

Inclusion Criteria:

1. Nurses (at least 50% from the south),

2. Primary Care/Family Physicians (at least 50% from the south),

3. Rural, low-income, minority men and women living in the south (income of $25K per year
or less and 70% of respondents will be Black, Latina, or Native American) and

4. Urban, low-income minority men and women living in the south (income of $25K per year
or less and 70% of respondents will be Black, Latina, or Native American).

Exclusion Criteria:

-

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: 100 Years
Countries
United States
Locations

Carol Belk Building
Greenville, North Carolina, United States

Investigator: Alice Richman

Contacts

Alice R Richman, PhD
252-328-6431
richmana@ecu.edu

Becky Welch, CPA, Study Chair
Assistant Vice Chancellor for Research Administration & Finance

East Carolina University
NCT Number
MeSH Terms
Coronavirus Infections