Official Title
Evaluation of Quickly Diagnostic Saliva Tests for SARS-CoV-2
Brief Summary

Coronavirus disease 2019 or COVID-19 is a highly contagious infectious disease. Symptoms of the disease are non-specific (fever, cough, dyspnea and fatigue), common with many seasonal viruses, which complicates the diagnosis. For mild forms, which represent the vast majority of cases, hospitalization is not necessary and treatment is symptomatic. However in more severe cases, hospitalization is required and sometimes even admission to an intensive care unit. Several diagnostic tests are already available, but they require, in all cases, the intervention of qualified health personnel to carry out the sample, which includes a risk of contagion and an expensive and time-consuming laboratory analysis and reagents. These tests are therefore not very suitable for massive screenings. We want to evaluate the performance of a detection test performed on a salivary sample in the diagnosis of SARS-CoV-2. This test will be non-invasive, performed without any analytical device and will restore its qualitative result "infected versus non-infected" in less than 1 hour (30min objective).

Detailed Description

Study taking place at the Montpellier University Hospital, comparing a salivary sample group
with active infection (participants) for SARS-COV2 with a salavary sample tested negative
(cured, convalescent and negative) for SARS-COV2 (healthcare workers ,participants)

Completed
SARS-CoV-2

Diagnostic Test: Sampling salivary

Collection of 1 to 2 ml of saliva

Eligibility Criteria

Inclusion Criteria:

- Control subjects (COV2- group): Participants ( Healthcare staff, patients and DRIVE
participants) negative for SARS-CoV-2

- Infected subjects (COV2 + group): Patients diagnosed positive for SARS-CoV-2 hospital
staff known to be positive and coming to do a control PCR DRIVE participants.

Exclusion Criteria:

- Eligibility Criteria:

Inclusion Criteria:

- Control subjects (COV2- group): Healthcare staff presumed and diagnosed negative for
SARS-CoV-2

- Infected subjects (COV2 + group): Patients diagnosed positive for SARS-CoV-2 hospital
staff known to be positive and coming to do a control PCR

Exclusion Criteria:

- Not affiliated with a French Social Security Systemscheme or equivalent system

- Persons deprived of their liberty, adult protected under guardianship or vulnerable
persons

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: 90 Years
Countries
France
Locations

UCH Montpellier
Montpellier, France

REYNES Jacques, PU PH, Principal Investigator
Montpellier Hospital

University Hospital, Montpellier
NCT Number
Keywords
Diagnosis test
Salivary sampling