Official Title
Evaluation of a Chest X-Ray AI Neural Network (RadGen SARS-CoV2 Detection System) for the Detection of RT-PCR Confirmed SARS-Cov2 Covid-19 Pneumonia
Brief Summary

This study investigates the diagnostic performance of an AI algorithm in the detection of COVID-19 pneumonia on chest radiographs.

Detailed Description

This is an international multi-center study. Chest radiographs (CXR) from different
participating centers will be collected to develop an AI algorithm to detect COVID-19
pneumonia. This will be tested on external hold out datasets from different centers using
SARS-CoV-2 by Real-Time Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR) Assay as
ground truth.

Unknown status
COVID19

Diagnostic Test: AI model

Deep Learning CNN model

Eligibility Criteria

Inclusion Criteria:

- All adult patients >18 years of age

- Attended any of the participating institutes between February 1, 2020 until September,
2020

- Underwent both RT-PCR testing and frontal CXR (within 48 hours of PCR testing) for
COVID-19 infection

- frontal CXR of patients pre-covid pandemic

Exclusion Criteria:

- Unavailability of patient demographics and clinical data

- Inconclusive RT-PCR results

- CXR considered to be of non-diagnostic quality by the clinical radiology research team
at each site

- CXR not in a retrievable or processable format for AI inference

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: 120 Years
Countries
Hong Kong
Locations

University of Hong Kong
Hong Kong, Hong Kong

Ensemble Group Holdings, LLC
NCT Number
MeSH Terms
COVID-19
Pneumonia