Official Title
Evaluation of Demographic and Clinical Parameters on Admission and Medications Used for Comorbidities in Patients With Covid-19 Pneumonia: A Single Center Experience in Turkey
Brief Summary

Investigators will recruit patients diagnosed with COVID-19 pneumonia between March 11th, 2020 and April 15th, 2020 in emergency, internal medicine and cardiology outpatient clinics, retrospectively and analyze their clinical and demographic features on admission in regard to their medications used for chronic diseases regularly.

Detailed Description

Covid-19 infections demonstrated a pandemic spread after January 2020 and their associations
with patient characteristics and comorbidities are intensely studied. Investigators also want
to find out potential relations between major medications taken for chronic diseases and
clinical parameters of patients with Covid-19 pneumonia.

For the study, investigators will recruit patients diagnosed with COVID-19 pneumonia between
March 11th, 2020 (the date at which the first case of Covid-19 in Turkey officially declared)
and April 15th, 2020 in emergency, internal medicine and cardiology outpatient clinics,
retrospectively. All of the demographic features, complaints on admission, reports of
computed tomography (CT) scans of the chest without intravenous contrast issued by the staff
radiologist, c-reactive protein (CRP) and complete blood count (CBC) values on admission will
be recorded retrospectively. Their polymerase chain reaction (PCR) test results will be
derived from the hospital records based on public health covid-19 database notifications and
list of medications taken regularly for more than 8 weeks before the diagnosis of COVID-19
pneumonia from the national pharmacy database. Information about other systemic diseases and
major medical conditions of patients will be procured from the medical histories gained by
relevant physicians. Patient taking each drug group will be compared to those not taking that
drugs in terms of clinical and demographical features mentioned above. Statistical analysis
will be performed by using SPSS software.

Completed
COVID-19

Drug: ACE Inhibitors and Calcium Channel Blockers

effect of drugs on patients with covid-19 pneumonia
Other Name: NSAID

Eligibility Criteria

Inclusion Criteria:

- Covid-19 pneumonia at least with typical infiltration on CT +/- positive PCR.

Exclusion Criteria:

- no typical infiltration and negative PCR results.

- not newly diagnosed.

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: 99 Years
Countries
Turkey
Locations

Vital Hospital
Bahcelievler, Istanbul, Turkey

Hasan Haciosman, Study Chair
academic staff, MD

Nisantasi University
NCT Number
Keywords
COVID-19 pneumonia
medication
comorbidity
MeSH Terms
COVID-19
Pneumonia
Calcium Channel Blockers
Calcium
Angiotensin-Converting Enzyme Inhibitors