In December 2019,a new type of pneumonia caused by the coronavirus (COVID-2019) broke out in Wuhan ,China, and spreads quickly to other Chinese cities and 28 countries. More than 70000 people were infected and over 2000 people died all over the world. There is no specific drug treatment for this disease. Considering that lung damage is related to both viral infection and burst of cytokines, our idea is to evaluate the efficacy and safety of escin as add-on treatment to conventional antiviral drugs in COVID-19 infected patients.
Drug: Escin
treatment with escin or escinate sodium
Drug: standard therapy
antiviral drugs
Inclusion Criteria:
- Aged between 18 and 75 years, extremes included, male or female
- Positivity to covid-19 screening test in molecular biology
- In escin group: Low response to standard treatment
- Ability to understand and the willingness to sign a written informed consent document
Exclusion Criteria:
- Female subjects who are pregnant or breastfeeding.
- patients with previous history to allergy
- patients meet the contraindications of escin
- Patients have any condition that in the judgement of the Investigators would make the
subject inappropriate for entry into this study.
- patients can't take drugs orally
Luca Gallelli
Catanzaro, Italy
Investigator: LUCA GALLELLI
Contact: 3339245656
gallelli@unicz.it
LUCA GALLELLI
3339245656 - 3339245656
gallelli@unicz.it