This study is to evaluate of the accuracy of biomarkers (i.e. circulating endothelial and immune activation markers) that indicate progression to severe disease in patients with suspected COVID-19 in the Emergency Department. It is a prospective observational study of patients presenting to emergency departments with a clinical suspicion of COVID19. All participants will have plasma samples collected for biomarker analysis, and will be tested for SARS-CoV-2 infection with a nasopharyngeal swab. Participants will be managed according to the best local practices.
Inclusion Criteria:
- Patients presenting with clinical suspicion of COVID-19 infection, as per UHN case
definition at the time of presentation
- Age >18 years
- Ability to provide verbal informed consent
Exclusion Criteria:
- Patients who are not suspected of COVID-19 infection, as per UHN definition at the
time of presentation
University Health Network
Toronto, Ontario, Canada
Investigator: Sharaniyaa Balachandran
sharaniyaa.balachandran@uhn.ca
Investigator: Shahid Husain, MD MS
Sharaniyaa Balachandran
416-340-4800 - 6549
sharaniyaa.balachandran@uhn.ca
Shahid Husain, MD MS, Principal Investigator
University Health Network, Toronto