Official Title
Effects of COVID-19 Induced Deconditioning After Long-term High Intensity Resistance Exercise in Older Men With Osteosarcopenia A Randomized Controlled Trial
Brief Summary

Osteosarcopenia designates the simultaneous presence of sarcopenia and osteopenia; both chronic conditions of advanced age. Dynamic-resistance exercise (DRT) might be the most powerful agent to fight osteosarcopenia. Indeed, in the present FrOST study, we clearly determine the positive effect of slightly adapted 18 month high-intensity (HIT)-DRT on bone mineral density (BMD), sarcopenia and other health related parameters in osteosarcopenic men. However, after a short training break, COVID-19 induced lock down prevented a re-start of the HIT resistance exercise training in the FrOST cohort. The aim of the present observational study is thus to determine the effects of 6 months of deconditioning on health related parameters under special regard of osteosarcopenia in this cohort of older men with osteosarcopenia.

Completed
Osteoporosis
Sarcopenia
Eligibility Criteria

Inclusion Criteria:

- participants of the FrOST study (NCT03453463)

Exclusion Criteria:

- medication and diseases with potential impact on study outcomes during the last 26
weeks.

Eligibility Gender
Male
Eligibility Age
Minimum: 74 Years ~ Maximum: 95 Years
Countries
Germany
Locations

Institute of Medical Physics, Friedrich Alexander University Erlangen-Nürnberg
Erlangen, Bavaria, Germany

wolfgang Kemmler, PhD, Principal Investigator
Institute of Medical Physics, Friedrich-Alexander University Erlangen-Nürnberg

Friedrich-Alexander-Universität Erlangen-Nürnberg
NCT Number
MeSH Terms
Osteoporosis
Sarcopenia