Several treatments have been used in during the Covid-19 pandemic of 2020. Using patients' registries from several hospitals in Paris, the investigators retrospectively analyzed associations between specific treatments, including but not limited to vaccines targeted against SARS-CoV-2, hydroxychloroquine, azithromycin, remdesivir, baricitinib, tocilizumab, sarilumab, lopinavir/ritonavir and oseltamivir; and clinical outcomes including, death and mechanical ventilation.
Several treatments have been used in during the Covid-19 pandemic of 2020. Using patients'
registries from several hospitals in Paris, the investigators retrospectively analyzed
associations between specific treatments, including but not limited to vaccines targeted
against SARS-CoV-2, hydroxychloroquine, azithromycin, remdesivir, baricitinib, tocilizumab,
sarilumab, lopinavir/ritonavir and oseltamivir; and clinical outcomes including, death and
mechanical ventilation.
Other outcomes of interest include: acute kidney injury, encephalopathy, need for intensive
care unit transfers.
Inclusion Criteria:
- admitted for severe Covid-19 pneumonia (i.e. requiring O2-support more than 6L/min
with SpO2<96%)
Exclusion Criteria:
- patients who were previously in ICU
- patients already hospitalized prior to study start date
- patients in palliative care
- lack of consent
Centre Hospitalier Intercommunal Robert Ballanger
Aulnay-sous-Bois, France
Centre Hospitalier Intercommunal Le Raincy-Montfermeil
Montfermeil, France
Joe-Elie Salem, MD, PhD, Study Chair
APHP