This is a double-blind placebo controlled trial that seeks to evaluate the impact of melatonin and vitamin C on symptoms and outcomes of patients with COVID-19.
Dietary Supplement: Vitamin C
1000mg Vitamin C, at bedtime
Other Name: ascorbic acid
Dietary Supplement: melatonin
10mg melatonin, at bedtime
Dietary Supplement: Placebo
Placebo at bedtime
Other: Symptom Survey
Daily symptom survey to be completed by patient electronically
Inclusion Criteria
- COVID-19 positive test (outpatient testing),
- Age >50 (chosen based greater risk for older patients to be vitamin deficient, age >65
not used so as not to be too restrictive in the inclusion criteria)
- Experiencing symptoms for <5 days prior to enrollment
- Able to read and write in English or Spanish
- Able to access REDCap daily
- Valid email address
- Current has a Lancaster General Health primary care physician
Exclusion Criteria
- COVID-19 test ordered pre-procedure for asymptomatic screening
- Currently taking vitamin C supplements
- Currently taking melatonin supplements
- Currently hospitalized
- Deceased
- Currently pregnant
- Currently incarcerated
Lancaster General Health
Lancaster, Pennsylvania, United States