In a cohort study, the investigators aim to compare confirmed COVID-19 patients with non-COVID-19 patients who undergo surgical treatment and study factors associated with good or bad outcomes.
Background A novel Coronavirus (SARS-CoV-2) was first detected in the Hubei Province in China
in December, 2019. The virus causes a severe respiratory disease (Coronavirus disease 2019,
COVID-19) that has rapidly spread worldwide. The COVID-19 pandemic is prognosed to affect a
majority of the world's population before the end of 2020. Throughout the course of the
pandemic, patients will continuously need essential healthcare, such as for acute surgical
conditions. How the clinical course and management of surgical conditions is influenced by
concomitant COVID-19 is largely unknown. There is an acute need for an improved evidence base
to inform treatment strategies and guide the management of this patient group.
Objectives
1. To compare confirmed COVID-19 patients with non-COVID-19 patients who undergo surgical
treatment and study factors associated with good or bad outcomes.
Methods The study will enrol consecutive patients that undergo surgical treatment in the
Stockholm Region. Data will be extracted from a series of linked electronic systems, such as
electronic healthcare records systems, and regional data systems. Collected data will include
routine clinical data, such as baseline characteristics, previous medical history, details on
care given at the hospital and data from follow-up visits. Endpoints include death, length of
hospital stay and complications, such as readmission, reoperation, sepsis, respiratory
failure, and number of days in the intensive care unit. Outcome data of patients with
confirmed COVID-19 will be compared to those of patients without COVID-19.
Dissemination and relevance To the best of the investigators knowledge, there has been no
previous comprehensive comparative research on patients with and without confirmed COVID-19
that undergo surgical treatment. The results will be disseminated through peer-reviewed
publications, aiming for journals with a rapid editorial process, preferably open access
journals. The findings are expected to increase the knowledge to establish best-treatment
strategies and improve outcomes, both for patients affected by COVID-19 and by future
epidemics.
Other: COVID-19 infection status
We will compare patients with/without confirmed COVID-19 infection
Inclusion Criteria:
- Patients that undergo surgical treatment in the Stockholm Region during the study
period
Exclusion Criteria:
-
Samtliga akutsjukhus i Region Stockholm
Stockholm, Sweden
Investigator: Andreas Älgå, MD, PhD
Contact: 0702463287
andreas.alga@ki.se
Andreas Älgå, MD, PhD
0702463287
andreas.alga@ki.se
Gabriel Sandblom, MD, PhD, Study Chair
Södersjukhuset AB, Stockholm, Sweden