Deep sedation in patients with COVID-19 may be challenging in many aspects. The use of an EEG-based protocol to guide deep sedation may be useful in this particular population, considering their unusually high sedation requirements. In the present trial, we aim to evaluate an EEG-based protocol to guide deep sedation in patients with COVID19, using to EEG derived parameters that are displayed in the BIS monitor: Suppression Rate and Spectral Edge Frequency. The protocol is designed to both minimize the suppression rate along with maintaining a spectral edge frequency over 10 Hz. The use of this protocol may reduce the amount of sedatives administered and, therefore, diminish the time needed for the weaning process.
Other: EEG based protocol for deep sedation
Protocol established to guide sedation drug dosification to maintain the patient with a Suppression Rate (SR) less than 1% and a Spectral Edge Frequency 95 over 10 Hz
Inclusion Criteria:
- Patients over 18 years old
- COVID-19 patient requiring mechanical ventilation
Exclusion Criteria:
- Contraindication to receive propofol or fentanyl
- Chronic Liver Disease Child C
- End-Stage Kidney Chronic Disease
Hospital Clinico de la Universidad de Chile
Santiago, RM, Chile