Official Title
The Effect of Early Prone Position on Prognosis in Acute Respiratory Failure Due to Coronavirus Disease 2019 Pneumonia
Brief Summary

the purpose of this study to evaluate the effect of early awake PP (prone position)application on oxygenation and intubation requirement in patients with acute respiratory failure due to coronavirus disease 2019 pneumonia.

Detailed Description

The first group (early prone position-EPP) created for our study was composed of patients who
received PP at least 12 hours early (with the first 48 hours) with the oxygen support of the
reservoir mask, and the second group (non-EPP ) patients who received oxygen with the
reservoir mask but could not be applied early PP due to the patient's incompatibility or
rejection.

Conventional oxygen therapy applied to all patients was given with a reservoir mask, aiming
at oxygen saturation 93% and above, at a flow rate of 6-15 L / min.

Despite all the treatments, the patients who have a follow-up with a respiratory acidosis ,
oxygen saturation value below 93%, applied non invasive mechanical ventilation, in case of
insufficient patient intubated and have invasive mechanical ventilation. In patients who had
regression of glasgow coma scale during follow-up, orotracheal intubation was performed and
invasive mechanical ventilation was performed.

Completed
Coronavirus Infection
Acute Respiratory Failure

Behavioral: prone position

to lay in prone position at least 12 hour in a day at ICU

Eligibility Criteria

Inclusion Criteria:

- Patients who developed acute respiratory failure due to coronavirus disease 2019
pneumonia

- received conventional oxygen therapy with reservoir mask oxygen at the stage of
admission to the intensive care unit

- older than 18 years old

Exclusion Criteria:

- patients with respiratory acidosis,

- partial oxygen pressure/fraction of inspired oxygen ratio below 150,

- Glasgow Coma Score (GKS) below 12 points,

- hemodynamic instability,

- primary pulmonary pathologies other than pneumonia (lung cancer, cardiopulmonary
edema, carcinogen syndrome, etc.)

- patients who underwent non-invasive mechanical ventilation(NIMV) or intubated from
admission to intensive care,

- those who underwent self prone position under 12 hours were not included in the study.

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: N/A
Countries
Turkey
Locations

Sisli Etfal Research and Training Hospital
Istanbul, Marmara, Turkey

ayse surhan cinar, Study Chair
chief of anesthesia department

Sisli Hamidiye Etfal Training and Research Hospital
NCT Number
Keywords
Coronavirus disease 2019
Prone position
MeSH Terms
Pneumonia
Coronavirus Infections
COVID-19
Respiratory Insufficiency
Respiratory Distress Syndrome