Official Title
Air Pollution and COVID-19 Mortality in Geriatric Patients: a Multicenter Study
Brief Summary

Epidemiological data have related particulate matter (PM), nitrogen dioxide (NO2) and ozone (O3) to COVID-19 morbidity and mortality at the population level. Air pollution may be related to an increase in the COVID-19 severity and lethality through its impact on chronic diseases such as cardiovascular and respiratory diseases and diabetes that are also the main comorbidities associated with COVID-19. Epidemiological studies using individual data are needed to provide more precise estimate of the association between air pollution exposure and COVID-19. In this multicenter prospective study, the investigators will analyze the number of deaths in COVID-19 confirmed cases in geriatric patients according to long-term exposure to air pollution, taking into account confounders such as diabetes, hypertension, age, and BMI. Exposure to air pollution will be estimated as the mean concentration of air pollutants at the residential address during the previous two years. In addition, the investigators will explore the relationship between short-term variations in air pollutants, relative humidity, temperature, UV radiations, pollen and the occurrence of COVID-19.

Completed
COVID-19 Confirmed Cases
COVID-19 Mortality
Eligibility Criteria

Inclusion Criteria:

- Patient over 60 years old (or dementia patient over 50 years old)

- Patient hospitalized in a geriatric department over the period from 2020/01/01 to
2020/06/01

- Patient who underwent RT-PCR SARS-CoV-2

- Patient (or trusted person/ legal guardian/curator, if applicable) who has given
consent to the re-use of his/her data (patient data) for research purposes

Exclusion Criteria:

None

Eligibility Gender
All
Eligibility Age
Minimum: 50 Years ~ Maximum: N/A
Countries
Belgium
France
Locations

Unité de neurologie-gériatrie, Hôpital Erasme, Cliniques Universitaires de Bruxelles
Bruxelles, Belgium

Unité de soins palliatifs gériatriques, Centre Hospitalier Départemental de Bischwiller
Bischwiller, France

Service de Gériatrie, Centre Hospitalier Départemental de Vendée
La Roche Sur Yon, France

Service de médecine aigüe gériatrique, Hôpital Nord Laennec, Hôpitaux Universitaires de Nantes
Nantes, France

Service de Gériatrie, Hôpitaux Bichat et Bretonnaux, Assistance Publique des Hôpitaux de Paris
Paris, France

Service de Médecine Interne et Gériatrie, Hôpitaux Universitaires de Reims
Reims, France

Service de Gériatrie, Hôpital de la Robertsau, Hôpitaux Universitaires de Strasbourg
Strasbourg, France

Service de médecine gériatrique, Hôpitaux Universitaires de Tours
Tours, France

Frédéric BLANC, MD, Principal Investigator
Hôpitaux Universitaires de Strasbourg

University Hospital, Strasbourg, France
NCT Number
Keywords
Air pollution
Covid-19
Respiratory viral diseases
PM- NO2-Ozone
MeSH Terms
COVID-19