Official Title
Longidutinal, Dynamic Analysis of COVID-19 Vaccine Induced Adaptive Immune Responses
Brief Summary

The coronavirus disease 2019 (COVID-19) caused by the infection of severe acuterespiratory syndrome coronavirus 2 (SARS-CoV-2),resulting in more than 82 millionconfirmed cases and caused around 1.8 million deaths, as of 2 January 2021. The ongoingpandemic still poses unprecedented global threat to public health system worldwide. OnDecember 31, 2020, the joint prevention and control agency of China Council announcedthat Sinopharm SARS-CoV-2 inactivated vaccine had been conditionally approved by NationalMedical Products Administration, and the protection rate was 79.34%. So far, more than198 vaccines were currently in preclinical or clinical development. The investigatorsaimed to initiate an observational cohort of healthy individuals injected with SARS-CoV-2Vaccine, which will perform a longitudinal, comprehensive analysis of the SARS-CoV-2vaccine Induced adaptive immune responses.

Unknown status
SARS-CoV-2
Vaccine
COVID-19
Eligibility Criteria

Inclusion Criteria:

- Healthy and aged between 18 to 59 years

Exclusion Criteria:

- High-risk epidemiology history within 14 days before enrollment

- SARS-CoV-2 specific IgG or IgM positive in serum

- Positive PCR test for SARS-CoV-2 from pharyngeal or anal swab samples

- Axillary temperature of more than 37·0°C

- Known allergy to any vaccine component

- Thyroid disease

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: 59 Years
Countries
China
Locations

Nanjing Drum Tower Hospital
Nanjing, Jiangsu, China

Investigator: Yuxin Chen

Investigator: Chao Wu

Contacts

Chao Wu, M.D., Ph.D
+8613809022921
dr.wu@nju.edu.cn

Yuxin Chen, Ph.D
+8617714413628
yuxin_chen2015@163.com

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
NCT Number
MeSH Terms
COVID-19