Given the current lack of effective COVID-19 treatment, it is necessary to explore alternative methods to contain the spread of the infection, focusing in particular on its mode of transmission. The modes of person-to-person transmission of SARS-CoV-2 are direct transmission, such as sneezing, coughing, transmission through inhalation of small droplets, and transmission through contact, such as contact with nasal, oral and eye mucous membranes. SARS-CoV-2 can also be transmitted directly or indirectly through saliva. The use of antiviral mouthrinses may be used as adjunctive therapy.
Device: mouthrinse with bêta-cyclodextrin and citrox
3 daily mouthrinses for 7 days
Device: mouthrinse without bêta-cyclodextrin and citrox
3 daily mouthrinses for 7 days
Inclusion Criteria:
- Clinical diagnosis of Covid-19 infection by the patient's general practitioner and
hospital doctor
- Clinical signs started less than 8 days ago.
- Virological confirmation
- Understanding and acceptance of the trial.
- Written agreement to participate in the trial
Exclusion Criteria:
- Pregnancy
- Breastfeeding
- Inability to comply with protocol
- Lack of written agreement
Clinic of the Protestant Infirmary in Lyon
Caluire-et-Cuire, France
Hospital Center Emile Roux
Le Puy en Velay, France
Hospital Center Saint Luc Saint Joseph
Lyon, France
Intercommunal Hospital Center of Mont de Marsan
Mont de Marsan, France
Florence Carrouel, Dr, Study Director
University Claude Bernard Lyon 1