Using Laser light to detect COVID 19 virus particles in deep throat swab / nasal swab samples.
The investigators will develop novel primers to detect single virus particles in patient
samples. The method involves the absorption of light by single virus particles giving a
specific pattern. The investigators will develop the device to create a microdroplet of
carrier fluid that is run through the trial device. The investigators will develop novel
binding receptors for preferential capture of Coronavirus.
The investigators will review the results of the novel test against the standard diagnostic
test and identify virus particles in test negative subjects.
The investigators will isolate the viral rna in test negative subjects and perform sequencing
to find novel mutations that are not detected by the current test.
Diagnostic Test: Novel laser inferometry test for CORONA virus
detection of virus particles by light absorbtion patterns.
Inclusion Criteria:
- clinical suspicion of coronavirus or staff member having a coronavirus test
Exclusion Criteria:
- unable to give written informed consent
Somerset NHS Foundation Trust
Taunton, Somerset, United Kingdom
Investigator: Karen Tanner
Contact: 01823342056
research@tst.nhs.uk