Official Title
Clinical Course of Cancer Patients Who Contracted COVID 19 Infection: An Observational Study
Brief Summary

It's an obsevational retrospective/prospective study. Analyzing the evolution of COVID 19 infection in cancer patients can provide interesting information in the management of these patients. For this reason, the purpose of this study is to implement a registry to describe and monitor cancer patients affected by COVID 19, the factors that are associated with an unfavorable evolution, to develop a strategy for the risk assessment of these patients and recommendations. relating to their treatment. Particular attention will be paid to patients suffering from urological tumors because the treatment followed by the patients would seem to expose them to a greater risk when they are infected with coronavirus, furthermore, from the literature it is clear that there may be a connection between sex hormones and ACE2 levels in the plasma. In fact, the estrons up-regulate the concentration of ACE2 in the circulation and this could be the reason why women would seem more protected than men once they contract the coronavirus infection

Detailed Description

Primary objectives:

- describe cancer patients with COVID-19 and their clinical course;

- identify predictors of the most severe clinical course;

- identify prognostic factors; Secondary objectives

- Monitor patients with urological tumors with particular attention;

- Dosing parameters of inflammation such as IL-6 and IFNα;

- Measure the ACE2 levels.

Patients with oncological pathology who contracted COVID 19 infection from January 1, 2020
until the WHO declaration of the end of the pandemic will be studied.

Unknown status
COVID19

Other: No intervention on patients

No intervention on patients

Eligibility Criteria

Inclusion Criteria:

- confirmation of COVID-19 in the laboratory (RT-PCR techniques);

- suspected cases of COVID-19; clinically diagnosed based on symptoms (fever> 37.5 °,
decrease in oximeter saturation by at least 5%, cough, diarrhea, otitis, dysgeusia,
myalgia, arthralgia, conjunctivitis and rhinorrhea) + close contact a COVID-19 subject
positive;

- asymptomatic cases; diagnosed based on positive swab results but without symptoms even
dead patients

Exclusion Criteria:

-

Eligibility Gender
All
Eligibility Age
Minimum: N/A ~ Maximum: N/A
Countries
Italy
Locations

Oncology Unit, Hospital Andrea Tortora
Pagani, Salerno, Italy

Investigator: Data Manager Oncology Unit
Contact: +390819213683
trialclinici.oncopagani@gmail.com

Contacts

Data Manager Oncology Unit
+390819213683
trialclinici.oncopagani@gmail.com

Giuseppe Di Lorenzo, Principal Investigator
Oncology Unit

Ospedale Andrea Tortora di Pagani
NCT Number
Keywords
Covid-19
Oncological patients
cancer
Coronavirus infection disease
MeSH Terms
Infections
COVID-19