During the new COVID-19 pandemic physicians all over the world have faced different challenges .Oxidative stress is a probable cause of multi organ failure in this setting which never has been evaluated in COVID-19 infection to the best of knowledge.Present study aimed to evaluate oxidative stress marker and redox system status in different COVID-19 patients regarding the severity of involvement.
Oxidative stress is a probable cause of multi organ failure in this setting which never has
been evaluated in COVID-19 infection to the best of knowledge.Present study aimed to evaluate
oxidative stress marker and redox system status in different COVID-19 patients regarding the
severity of involvement. Demographic and lab data of 60 COVID-19 confirmed positive cases
gathered .These patients divided in to two arms: 1- severe COVID-19 which were intubated or
admitted in intensive care unit due to severe hypoxia 2- non-severe COVID-19 patients which
were not hypoxic and admitted in ward with no need to invasive oxygenation. All patients had
positive RT-PCR positive nasopharyngeal swab results for COVID-19 or Lung CT scan compatible
with COVID-19. Malondialdehyde(MDA) , Biopterin, Neopterin, SOD, Glutathione levels would be
checked by ELISA tests and compared between these two groups and healthy controls.
Diagnostic Test: Oxidative Stress ELISA Kit
Checking oxidative stress markers and redox system status
Inclusion Criteria:
- more than 18 years old
- positive RT-PCR COVID-19
- compatible lung CT with COVID-19
Exclusion Criteria:
- not signing informed consent
- using antioxidants
- using statins
Nooshin Dalili
Tehran, Iran, Islamic Republic of
Investigator: Nooshin Dalili, Dr
Contact: 00989122404331
nooshindalili4@gmail.com
Nooshin Dalili
00989122404331
nooshindalili4@gmail.com
Dalili, Principal Investigator
SBMU