Official Title
Comprehensive Clinical, Virological, Microbiological, Immunological and Laboratory Monitoring of Patients Hospitalized With Coronavirus Disease 2019 (COVID-19)
Brief Summary

COVID-19 may cause another world-wide epidemic. This study is divided into 2 arms: (1)Prospective longitudinal observational study involving patients with laboratory-confirmedCOVID-19 and (2) Retrospective study on patients with laboratory-confirmed COVID-19.Arm 1:We will collect EDTA blood, stool samples, rectal swab, urine, saliva, and specimens fromupper respiratory tract (nasopharyngeal aspirate or flocked swab), and lower respiratorytract (sputum or tracheal aspirate) on daily, alternate day, or weekly basis asappropriate.Arm 2:The remainder of specimens that were submitted for laboratory investigation as part ofclinical management will be retrieved. Those specimens will only be used after allclinically indicated testing and confirmation procedures have been completed. Assistancefrom the Public Health Laboratory Service, Department of Health, will be invited toretrieve samples as well as participate in this study.Patients hospitalized for pneumonia in medical wards and ICU at the Prince of WalesHospital tested negative for COVID-19 will be recruited as controls.Understanding the clinical, virological, microbiological and immunological profiles ofthis infection is urgently needed to facilitate its management and control.

Unknown status
Coronavirus Infections

Other: No intervention

No intervention

Eligibility Criteria

Inclusion Criteria:

- Case are adults age ≥ 18 years old admitted to hospital with laboratory confirmed
COVID-19

- Controls are patients admitted for community-acquired pneumonia

Exclusion Criteria:

- Patients who refuse to consent for study

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: N/A
Countries
Hong Kong
Locations

Prince of Wales Hospital
Sha Tin, Hong Kong

Contacts

Paul CHAN
+852 35053339
paulkschan@cuhk.edu.hk

Chinese University of Hong Kong
NCT Number
Keywords
SARS-CoV-2
Coronavirus disease 2019
MeSH Terms
Coronavirus Infections
COVID-19