The objectives of this study are to characterise immune responses in people with CoV-SARS-2 infection and use this knowledge to advance vaccine design, treatment options, and diagnostic reagents. Eligible participants will include people diagnosed with SARS-CoV-2 infection, and may include recently returned travellers and non-travellers in the community presenting to tertiary hospital healthcare facilities. Recruitment will be opportunistic, and sampling intensity may vary depending on the phase of the outbreak. Participants can be enrolled at any timepoint (up to 6 months) following diagnosis of SARS-CoV-2 infection (COVID-19). Blood samples and clinical data will be collected.
Other: Biological sample and clinical data collection
Plasma and serum will be collected at day 0, day 7, day 14, 1 month and 4 months post diagnosis. Clinical data related to COVID-19 diagnosis, symptoms, and outcomes will be collected.
Inclusion Criteria:
- Main cohort
1. Diagnosed with CoV-SARS-2 infection
2. 16 years of age or older
3. Have provided informed consent Paediatric cohort
1. Diagnosed with CoV-SARS-2 infection
2. Less than 16 years of age
3. Informed consent provided by parent or caregiver
Exclusion Criteria:
Main cohort
1. 15 years of age or younger
2. Inability or unwillingness to provide informed consent or abide by the
requirements of the study Paediatric cohort
1. 16 years of age or older
2. Inability or unwillingness of parent or caregiver to provide informed consent or
abide by the requirements of the study -
NSW Health Pathology
Randwick, New South Wales, Australia
Prince of Wales Hospital
Randwick, New South Wales, Australia
Sydney Children's Hospital
Randwick, New South Wales, Australia
Blacktown Hospital
Blacktown, Australia
Royal Prince Alfred Hospital
Camperdown, Australia
St Vincent's Hospital
Darlinghurst, Australia
Northern Beaches Hospital
Frenchs Forest, Australia
Royal North Shore Hospital
Saint Leonards, Australia
Westmead Hospital
Westmead, Australia
Rowena Bull
0293850900
r.bull@unsw.edu.au
Marianne Martinello
0293850900
mmartinello@Kirby.unsw.edu.au