A Clinical Study to Assess the Natural History of COVID-19 and Effects of KB109 and Supportive Self-care in Outpatients With Mild-to-moderate COVID-19

Inclusion Criteria:

- Be male or female, ≥18 years of age

- Be willing and able to give informed consent

- Screening/Randomization telemedicine visit within 2 days of testing positive test for
COVID-19

- Having self-reported fever or cough for not more than 72 hours prior to COVID-19
testing

- Mild to moderate COVID-19

- Able to adhere to the study visit schedule and other protocol requirements.

Exclusion Criteria:

- Patients who are hospitalized for in-patient treatment or currently being evaluated
for potential hospitalization at the time of informed consent for conditions other
than COVID- 19

- History of chronic lung disease

- Ongoing requirement for oxygen therapy

- Shortness of breath in resting position

- Diagnosis of sleep apnea requiring Bilevel Positive Airway Pressure (BIPAP) /
Continuous Positive Airway Pressure (CPAP)

- Female patients who are pregnant, trying to become pregnant or lactating

- Is considered, in the opinion of the PI, to be unlikely for any reason to be able to
comply with study procedures