Official Title
Characterization of the Clinical, Biological and Histological Pulmonary and Renal Damage Associated With the SARS-CoV-2 Syndrome in Patients Admitted in the Intensive Care Unit
Brief Summary

Renal damage in patients hospitalized for ARDS in the ICU can also be related to multiple causes including, but not limited to, the consequences of hemodynamic fluctuations in these patients or the use of nephrotoxic drugs responsible for acute post-ischemic or toxic tubular necrosis. Frequently observed abnormalities of cioagumation may also have a potential impact on renal structures, particularly glomerular capillaries. The researchers wish to characterize and phenotype the renal impairment of patients hospitalized in intensive care with tables of severe Covid19 infections in ARDS: clinical, biological and histological (by performing post-mortem biopsies). Translated with www.DeepL.com/Translator (free version)

Unknown status
Acute Respiratory Distress Syndrome
Eligibility Criteria

Inclusion Criteria:

- Patients over 18 years of age

- Diagnosed Covid-19 by RT PCR

- Hospitalized in intensive care for management of complications related to Covid-19
from March 1, 2020 to April 20, 2020

- Patient not having expressed his or her opposition, after information, to the re-use
of his or her data for the purposes of this research.

Exclusion Criteria:

- Subject who expressed opposition to participating in the study

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: N/A
Countries
France
Locations

Service Reanimation Medicale
Strasbourg, France

Investigator: Ferhat MEZIANI, MD, PhD
Contact: 33 3 69 55 10 24
ferhat.meziani@chru-strasbourg.fr

Investigator:

Contacts

Ferhat MEZIANI, MD, PhD
33 3 69 55 10 24
ferhat.meziani@chru-strasbourg.fr

Saïd CHAYER, PhD, HDR
33 3 88 11 66 90
said.chayer@chru-strasbourg.fr

University Hospital, Strasbourg, France
NCT Number
Keywords
ARDS
Covid-19
SARS-CoV-2
Inflammatory cytokine
Sepsis
ICU
Tbular necrosis
Ischemia
Pulmonary damage
Renal damage
Kidney damage
MeSH Terms
Respiratory Distress Syndrome
Respiratory Distress Syndrome, Newborn
Acute Lung Injury
Syndrome