Official Title
Cardiac Dysfunction in Critically Ill Patients With COVID-19
Brief Summary

Cardiac dysfunction has been reported to be common in patients infected with COVID-19. The aim of this study is to evaluate the clinical importance of cardiac dysfunction in critically ill patients infected with COVID-19.

Detailed Description

Cardiac dysfunction has been reported to be common in patients infected with COVID-19. The
aim of this study is to evaluate the clinical importance of cardiac dysfunction in critically
ill patients with COVID-19. Patients admitted to the intensive care unit, with COVID-19 are
examined with echocardiography for assessment of left and right ventricular dysfunction
within 72 hours from admission and repeated after four to seven days.

Cardiac dysfunction was defined as having either left ventricular (LV) dysfunction, defined
as having an ejection fraction <50% and/or regional hypokinesia, or right ventricular (RV)
dysfunction, defined as having a tricuspid annular plane excursion (TAPSE) <17mm or a
moderate/severe RV dysfunction assessed visually.

The cardiac biomarkers troponin and NTproBNP and clinical data are recorded at time of each
echo. Mortality status is recorded at 30 days.

Completed
COVID19
Left Ventricular Dysfunction
Right Ventricular Dysfunction
Pulmonary Hypertension

Diagnostic Test: Echocardiography

Echocardiography for assessment of cardiac function

Eligibility Criteria

Inclusion Criteria: Patients admitted to the intensive care unit infected with COVID-19

Exclusion Criteria:

-

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: 99 Years
Countries
Sweden
Locations

Södersjukhuset
Stockholm, Region Stockholm, Sweden

North Älvsborg County Hospital
Trollhättan, Västra Götalandsregionen, Sweden

Sahlgrenska University Hospital/Mölndal
Gothenburg, Västra Götaland, Sweden

Sahlgrenska University Hospital/Östra
Gothenburg, Västra Götaland, Sweden

Sahlgrenska University Hospital
Gothenburg, Västra Götaland, Sweden

Jonatan Oras, MD, PhD, Principal Investigator
Sahlgrenska University Hospital, Sweden

Sahlgrenska University Hospital, Sweden
NCT Number
MeSH Terms
COVID-19
Hypertension, Pulmonary
Ventricular Dysfunction
Ventricular Dysfunction, Left
Ventricular Dysfunction, Right